Kit for determining peroxidase-positive white blood cells
Most human ejaculates contain leukocytes, and the predominant form of leukocytes in human semen are peroxidase-positive granulocytes. The excessive presence of these cells (leukocytospermia) may indicate an infection of the reproductive tract. Leukocytospermia may also be associated with sperm profile defects (reduced sperm motility and DNA integrity, increased sperm viscosity, as well as loss of sperm function due to oxidative stress and/or secretion of cytotoxic cytokines by these white blood cells). Although leukocytospermia is not an absolute indication of infertility, this condition is observed in an average of 10-20% of all infertile men.
When the threshold of one million peroxidase-positive white blood cells per ml of ejaculate is exceeded, microbiological tests should be carried out to investigate possible infection of the accessory glands. Evaluation of accessory gland markers can provide additional useful information on the proper functioning of the epididymis (EpiScreen Plus, FertiPro NV), seminal vesicles (Fructose Test, FertiPro NV) or prostate. It is important to note that the absence of leukocytes does not exclude the possibility of infection of the accessory glands.
LeucoScreen Plus is a semi-quantitative, non-automated histochemical and diagnostic kit for the determination of peroxidase-positive white blood cells in human semen.
LeucoScreen Plus has a shelf life of 12 months from the date of manufacture. Information on product composition is available in the safety data sheet.