Test for anti-sperm antibodies
Sperm do not enter the bloodstream and, under normal conditions, the male reproductive system does not contain anti-sperm antibodies. However, when the blood-testis barrier is breached, the immune system can detect mature spermatozoa as antigenic and form anti-sperm antibodies that cause sub-fertility or infertility. Anti-sperm antibodies belong to two immunological classes: IgA and IgG antibodies, and may be present in the sperm sample as well as in male blood serum. Anti-sperm antibodies are also sometimes present in female blood serum. IgG anti-sperm antibodies are clinically associated with immunological infertility, so screening can help assess a couple's infertility.
The SpermMar IgG test is a semi-quantitative, non-automated diagnostic kit for the detection of IgG class anti-sperm antibodies on spermatozoa in human semen or serum. It is a rapid, easy-to-use microscopic test for infertile couples.
The test can be performed on a fresh, untreated human semen sample when using the direct SpermMar Test IgG test, or on human blood serum (from men and women) when using the indirect SpermMar Test IgG test. The SpermMar Test IgG can help assess a couple's infertility diagnosis and management.
The SpermMar IgG test has a shelf life of 18 months from the date of production. Information on product composition can be found in the safety data sheet.